The Applied Bioinformatics Core (ABC) is a central service group that specializes in providing data management and analysis support to large genomic centers and research groups. The objective of the core is to provide analytical capabilities to support and advance biomedical research.
We have ample expertise analyzing biological data from diverse types of experiments including, but not limited to, high-throughput genomic assays.
We have extensive experience in building standardized workflows as well as customized, in-depth analyses with emphasis on thorough quality control and statistical rigor.
We perform detailed computational analyses that are driven by specific biological questions defined by the investigators.
We provide extensive reports with publication-ready images as well as the analysis source code.
The example projects should give you an impression of the most commonly performed analyses - we are by no means limited to them and are happy to tackle new challenges. Please contact us at firstname.lastname@example.org for inquiries.
Single-cell RNA-seq | Spatial transcriptomics | CITE-seq | Differential gene expression analysis with bulk RNA-seq | General RNA biology assays such as CLIP-seq or PRO-seq
ChIP-seq | ATAC-seq | Reduced representation bisulfite sequencing (RRBS) or targeted methylation | Whole Genome Bisulfite sequencing
Variant calling and annotation | Evolution of viral sequences | Classifications of pathogens
GO term enrichments | Gene set enrichments | Pathway Analyses | DNA motifs | Integration of diverse data sets
Large-scale automation of analysis pipeline | Distribution and management of large datasets | Shiny apps
Walk-in clinic | Hands-on workshops | Meetings for coding tips exchange
Regularly held, intensive 12-hours-long courses open to members of the Tri-Institutional network
Monthly meetings to foster exchange of coding tips and tricks – open to anyone
Bioinformatics Software Engineer
Computational Biology Associate
Education and Outreach Coordinator
Senior Staff Associate of Computational Genomics
The Applied Bioinformatics Core (ABC) at Weill Cornell Medicine (WCM) in New York City is seeking a highly skilled computational biologist with a strong analytical background, driven to tackle the mysteries of biology with high-throughput data. We are looking for a bright and motivated person to join our team of experienced bioinformaticians.
The ABC is a well-established central service group located within the thriving Tri-I research environment created by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, and Rockefeller University. We provide analytical capabilities to support the cutting-edge biomedical research at WCM spanning virtually all areas of basic and biomedical science. Faculty and staff at this core facility have extensive expertise analyzing biological data from diverse types of high-throughput experiments, building standardized workflows as well as custom-tailored analyses with an emphasis on thorough quality control and statistical rigor. .
As a computational genomic scientist at the ABC, you will perform in-depth analyses of high-throughput data (single-cell and bulk RNA-seq, CITE-seq, ATAC-seq, ChIPseq/CUT&TAG, WGBS, etc.) to address a multitude of biological or clinical questions at the forefront of research across the WCM community. Central to this position is the ability to quickly develop a deep understanding of the underlying biology that each project addresses and of the scope and limitations of the individual experimental methods that are used. We are looking for candidates with deep knowledge of genomics, cell biology, and experimental protocols related to DNA sequencing and/or other ‘omics data types who are passionate about science and data analysis.
Qualifications we are looking for: